By scholarshipswithaakash@gmail.com 
Looking to pursue cutting-edge neuroscience research in one of Europe’s most vibrant locations? A PhD in RNA Localization in Drosophila Brain is now open for applications at the Institut de Biologie Valrose (iBV), University Côte d’Azur in Nice, France. This is a fully funded 3-year PhD opportunity starting in early fall 2025, open to motivated international candidates with a passion for RNA biology, neuroscience, and advanced imaging.
🔬 Project Title: Cellular Mechanisms Underlying RNA Localization in the Drosophila Brain
📍 Location: Institut de Biologie Valrose (iBV-UMR7277), Nice, France
🧠 Lab: Besse Group – RNA Localization and Neuronal Circuits
📅 Start Date: Fall 2025
💰 Funding: Fully funded for 3 years
🔍 PhD in RNA Localization in Drosophila Brain
The main objective of this PhD in RNA Localization in Drosophila Brain is to understand how specific classes of messenger RNAs (mRNAs) are transported and localized within neuronal sub-compartments. These RNA molecules are essential for synaptic plasticity and memory formation, and the mechanisms of their spatial distribution remain a central question in molecular neuroscience.
The student will join the ERC-recognized Besse Lab at iBV, which specializes in mRNA dynamics, axonal transport, RNA granules, and neural activity. The work involves a powerful combination of in vivo Drosophila genetics, imaging, biochemistry, and functional behavioral assays.
🧠 Project Overview – RNA Dynamics in the Neuronal Brain
The Besse Lab’s research addresses the molecular underpinnings of memory circuits in the brain. This PhD in RNA Localization in Drosophila Brain will explore:
- How mRNAs assemble with regulatory proteins into macromolecular complexes
- How these complexes are transported and localized in neuronal subdomains like axons
- The spatiotemporal regulation of mRNA translation in response to neuronal activity
- The role of cytoskeletal elements, including actin, in RNA trafficking and synaptic modulation
Model organism: Drosophila melanogaster (fruit fly)
Experimental toolkit:
- 🧪 In vivo live-cell imaging
- 🧬 In vivo RIP-seq and RNA-protein interactions
- 🔬 High-throughput microscopy
- ⚙️ In vitro reconstitution assays
This project will culminate in a comprehensive understanding of how subcellular mRNA localization influences neural circuit function and memory.
🧬 Candidate Profile – Who Can Apply?
The ideal candidate for this PhD in RNA Localization in Drosophila Brain should have:
✅ A Master’s degree in Molecular Biology, Neuroscience, Cell Biology, or a related field
✅ Experience (or strong interest) in RNA biology, neuronal circuits, or Drosophila genetics
✅ Familiarity with microscopy, bioinformatics, or imaging techniques
✅ Strong motivation and ability to work independently
✅ Good communication skills in English (both written and spoken)
✅ Passion for fundamental research and collaborative science
International students are strongly encouraged to apply. The institute and lab provide a multicultural, English-speaking environment.
🏫 Research Environment – Institut de Biologie Valrose (iBV)
Located on the Valrose campus of the University Côte d’Azur in Nice, the iBV is one of France’s leading research institutes for life sciences, especially neuroscience and genetics.
The institute offers:
- 🧪 Cutting-edge research facilities
- 🔬 Advanced light microscopy & live-cell imaging platforms
- 🧬 State-of-the-art cytometry, bioinformatics, and genomics support
- 🌍 A dynamic international research community
- 🏖 A stunning Mediterranean setting in Nice, with an affordable and high-quality lifestyle
💰 Funding & Support
The position is fully funded for 3 years, with:
💼 Monthly stipend according to French national PhD standards
📚 Research and lab materials fully covered
📈 Travel and conference participation opportunities
👩🏫 Access to professional development training and thesis supervision
📝 How to Apply
Interested in applying for this PhD in RNA Localization in Drosophila Brain? Here’s how:
📧 Email your application to:
Florence Besse → florence.besse@univ-cotedazur.fr
📄 Include the following in your application (PDF format):
- Updated CV
- Description of research interests and accomplishments
- Contact info for at least 2 referees
- Optional: publications or writing samples
📅 Deadline: Applications will be reviewed on a rolling basis. Selection is expected to be finalized by early September 2025. Apply early!
📚 Relevant Publications from the Lab
🧠 Nature Communications (2025): Axonal RNA localization is essential for long-term memory
🔬 Trends in Neurosciences (2023): RNA granules in neuronal plasticity and disease
🧬 Nature Communications (2019): Drosophila prion-like proteins and RNP granule transport
These publications reflect the lab’s commitment to high-impact science and their leading role in RNA neurobiology.
🔗 Official Resources & Internal Link
- Lab page: Besse Group
- Institute site: Institut de Biologie Valrose
- 🧭 Related Scholarships: https://scholarshipswithaakash.site
Need help with your PhD application (CV, SOP, proposal, etc.)?
📧 Email us: scholarshipswithaakash@gmail.com
🌟 Why Apply?
This PhD in RNA Localization in Drosophila Brain offers:
✔️ A funded opportunity in an elite European research center
✔️ A chance to train in diverse techniques (RNA, imaging, genetics, bioinformatics)
✔️ An inspiring academic community and Mediterranean lifestyle
✔️ Real contribution to understanding brain function and memory
If you’re passionate about RNA biology and neuroscience, this is your chance to make a lasting impact!
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